Advanced Free Radical Science

Publications

Apr. 2024-Mar. 2025: [3] Shishido S. The crystalline structures of zirconia influence its material properties. Official publication of the Japanese Society of Computer Aided Dentistry, 12: 7-12, 2024
[2] 中村圭祐. 歯科医療分野における微生物制御：1.開講にあたって. 日本防菌防黴学会誌, 52: 169-171, 2024
[1] 菅野太郎, 石山希里香, 中村圭祐. ブルーラジカル P-01 & ペリミル. 歯界展望, 143: 760-766, 2024
Apr. 2023-Mar. 2024: [6] Lehrkinder A, Rydholm O, Wänström A, Nakamura K, Örtengren U. The formation of cariogenic plaque to contemporary adhesive restorative materials - an in vitro study. Odontology, e-pub ahead of print, 2024
Open Acess
[5] Kurihara A, Nakamura K, Shishido S, Inagaki R, Harada A, Kanno T, Egusa H. Mechanism underlying ultraviolet-irradiation-induced discoloration of dental zirconia ceramics stabilized with 3 and 5 mol% yttria. Ceram Int, 50:12136-12145, 2024
[4] Shishido S. A case report of esthetic and occlusal recovery using dental implants and fixed prostheses in a patient with multiple missing teeth, Annal Jpn Prosthodont Soc, 16: 139-142, 2024
[3] Shishido S, Inagaki R, Kanno T, Svanborg P, Barkarmo S, Örtengren U, Nakamura K. Residual stress associated with crystalline phase transformation of 3–6 mol% yttria-stabilized zirconia ceramics induced by mechanical surface treatments. J Mech Behav Biomater Med. 146:106067, 2023
PubMed, Journal site
[2] Shirato M, Takida Y, Kanno T, Matsuura H, Niwano Y, Minamide H, Nakamura K. Mutagenicity assessment of high-power 1.6 THz pulse laser radiation. Photochem Photobiol. 100: 146-158, 2024
PubMed
[1] 岡谷泰佑, 横山雄基, 宍戸駿一, 中村圭祐, 金森義明. ワイヤグリッド偏光子付き光ファイババンドルの作製と歯質判別への応用. 電気学会論文誌E（センサ・マイクロマシン部門誌）, 143: 192-199, 2023
Journal site
Apr. 2022-Mar. 2023: [3] Niwano Y, Kohzaki H, Shirato M, Shishido S, Nakamura K. Metabolic fate of orally ingested proanthocyanidins through the digestive tract. Antioxidants, 12: 17, 2023
PubMed, Open Access
[2] Shirato M, Nakamura K, Tenkumo T, Niwano Y, Kanno T, Sasaki K, Lingström P, Örtengren U. Inhibition of tooth demineralization caused by Streptococcus mutans biofilm via antimicrobial treatment using hydrogen peroxide photolysis. Clin Oral Invest, 27: 739-750, 2023
PubMed
[1] Harai T, Mizutani M, Shishido S, Nakamura K, Ohmori H, Konno T, Kuriyagawa T. Low-temperature degradation of yttria-stabilized zirconia treated with pulsed laser and annealing techniques. Precis Eng, 80: 45-56, 2023
Journal site
Apr. 2021-Mar. 2022
Apr. 2020-Mar. 2021: [4] Xiang C, Tenkumo T, Ogawa T, Kanda Y, Nakamura K, Shirato M, Sokolova V, Epple M, Kamano Y, Egusa H, Sasaki K. Gene transfection achieved by utilizing antibacterial calcium phosphate nanoparticles for enhanced regenerative therapy. Acta Biomater, 119: 375-389, 2020
PubMed
[3] Nakamura K, Shirato M, Shishido S, Kanno T, Niwano Y, Sasaki K, Lingström P, Örtengren U. Reactions of dental pulp to hydrogen peroxide photolysis-based antimicrobial chemotherapy under ultraviolet-A irradiation in rats. J Photochem Photobiol B, 212:112042, 2020
PubMed
[2] Harada A, Shishido S (co-first author), Barkarmo S, Inagaki R, Kanno T, Örtengren U, Egusa H, Nakamura K. Mechanical and microstructural properties of ultra-translucent dental zirconia ceramic stabilized with 5 mol% yttria. J Mech Behav Biomed Mater, 111: 103974, 2020
PubMed
[1] Tenkumo T, Aobulikasimu A, Asou Y, Shirato M, Shishido S, Kanno T, Niwano Y, Sasaki K, Nakamura K. Proanthocyanidin-rich grape seed extract improves bone loss, bone healing, and implant osseointegration in ovariectomized animals. Sci Rep, 10: 8812, 2020
PubMed, Open Access
Apr. 2019-Mar. 2020: [3] Tenkumo T, Ishiyama K, Prymak O, Nakamura K, Shirato M, Ogawa T, Miyashita M, Takahashi M, Epple M, Kanno T, Sasaki K. Bactericidal activity and recovery effect of hydroxyl radicals generated by ultraviolet irradiation and silver ion application on an infected titanium surface. Sci Rep, 10: 8553, 2020
PubMed, Open Access
[2] Franco-Tabares S, Wardecki D, Nakamura K, Ardalani S, Hjalmarsson L, Stenport V, Johansson CB. Effect of airborne-particle-abrasion and polishing on novel translucent zirconias: Surface morphology, phase transformation and insights into bonding. J Prosthodont Res, 65: 97-105, 2021
J-Stage
[1] Shirato M, Nakamura K, Tenkumo T, Kano Y, Ishiyama K, Kanno T, Sasaki K, Niwano Y, Matsuura H. Oral mucosal irritation potential of antimicrobial chemotherapy involving hydrogen peroxide photolysis with high-power laser irradiation for the treatment of periodontitis. J Photochem Photobiol B, 201: 111633, 2019
PubMed
Apr. 2018-Mar. 2019: [10] Nakamura K, Shirato M, Tenkumo T, Kanno T, Westerlund A, Örtengren U, Sasaki K, Niwano Y. Hydroxyl radicals generated by hydrogen peroxide photolysis recondition biofilm-contaminated titanium surfaces for subsequent osteoblastic cell proliferation. Sci Rep, 9: 4688, 2019
PubMed, Open Access
[9] Tenkumo T, Fuji T, Ikawa M, Shoji S, Sasazaki H, Iwamatsu-Kobayashi Y, Okuyama Y, Matsui H, Shiraishi N, Furuuchi T, Higuchi K, Hashimoto W, Takeuchi Y, Simauchi H, Sasaki K. Introduction of integrated dental training jaw models and rubric criteria. Eur J Dent Educ, 23: e17-e31, 2018
PubMed
[8] Nakazawa K, Nakamura K, Harada A, Shirato M, Inagaki R, Örtengren U, Kanno T, Niwano Y, Egusa H. Surface properties of dental zirconia ceramics affected by ultrasonic scaling and low-temperature degradation. PLoS One, 13, e0203849, 2018
PubMed, Open Access
[7] Shishido S, Miyano R, Nakashima T, Matsuo H, Iwatsuki M, Nakamura K, Kanno T, Egusa H, Niwano Y. A novel pathway for the photooxidation of catechin in relation to its prooxidative activity. Sci Rep, 8: 12888, 2018
PubMed, Open Access
[6] Nakamura K, Tenkumo T, Mokudai T, Shirato M, Ishiyama K, Kanno T, Sasaki K, Niwano Y. Potential adverse effects of antimicrobial chemotherapy based on ultraviolet-A irradiation of polyphenols against the oral mucosa in hamsters and wounded skin in rats. J Photochem Photobiol B, 187: 96-105, 2018
PubMed
[5] Nakamura K, Ankyu S, Nilsson F, Kanno T, Niwano Y, Vult von Steyern P, Örtengren U. Critical considerations on load-to-failure test for monolithic zirconia molar crowns. J Mech Behav Biomed Mater, 87: 180-189, 2018
PubMed
[4] Ogawa T, Wang S, Zheng S, Miyashita M, Tenkumo T, Gu Z, Lian W, Sasaki K. The effect of low-magnitude high-frequency loading on peri-implant bone healing and implant osseointegration in beagle dogs. J Prosthodont Res, 62: 497-502, 2018
PubMed
[3] Tenkumo T, Vanegas Sáenz JR, Nakamura K, Shimizu Y, Sokolova V, Epple M, Kamano Y, Egusa H, Sugaya T, Sasaki K. Prolonged release of bone morphogenetic protein-2 in vivo by gene transfection with DNA-functionalized calcium phosphate nanoparticle-loaded collagen scaffolds. Mater Sci Eng C, 92: 172-183, 2018
PubMed
[2] Ankyu S, Nakamura K, Harada A, Inagaki R, Katsuda Y, Kanno T, Niwano Y, Örtengren U, Egusa H. Influence of microscale expansion and contraction caused by thermal and mechanical fatigue on retentive stregnth of CAD/CAM-generated resin-based composite crowns. J Mech Behav Biomed Mater, 86: 89-97, 2018
PubMed
[1] Hao Z, Ma Y, Liu W, Meng Y, Nakamura K, Shen J, Wang H. Influence of low-temperature degradation on the wear characteristics of zirconia against polymer-infiltrated ceramic-network material. J Prosthet Dent, 120: 596-602, 2018
PubMed
Apr. 2017-Mar. 2018: [7] Vanegas Sáenz JR, Tenkumo T, Kamano Y, Egusa H, Sasaki K. Amiloride-enhanced gene transfection of octa-arginine functionalized calcium phosphate nanoparticles. PLoS One, 12: e0188347, 2017
PubMed, Open Access
[6] Jin G, Asou Y, Ishiyama K, Okawa A, Kanno T, Niwano Y. Proanthocyanidin-rich grape seed extract modulates intestinal microbiota in ovariectomized mice. J Food Sci, 83: 1149-1152, 2018
PubMed
[5] Jin G, Aobulikasimu A, Piao J, Aibibula Z, Koga D, Ochi H, Ishiyama K, Kanno T, Niwano Y, Okawa A, Asou Y. Proanthocyanidin-rich grape seed extract prevent estrogen deficiency-induced metabolic disorders. J Med Dent Sci, 62: 45-50, 2018
J-Stage
[4] Niwano Y, Konno K, Matayoshi T, Nakamura K, Kanno T, Sasaki K. Oral mucosal irritation study in hamster to evaluate a therapeutic apparatus using hydrogen peroxide photolysis for periodontitis treatment. Regul Toxic Pharmacol, 90: 206-213, 2017
PubMed
[3] Kanno T, Nakamura K, Ishiyama K, Yamada Y, Shirato M, Niwano Y, Kayaba C, Ikeda K, Takagi A, Yamaguchi T, Sasaki K. Adjunctive antimicrobial chemotherapy based on hydrogen peroxide photolysis in non-surgical treatment for moderate to severe periodontitis: a randomized clinical trial. Sci Rep, 7: 12247, 2017
PubMed, Open Access
[2] Shirato M, Nakamura K, Kanno T, Lingström P, Niwano Y, Örtengren U. Time-kill kinetic analysis of antimicrobial chemotherapy based on hydrogen peroxide photolysis against Streptococcus mutans biofilm. J Photochem Photobiol B, 173: 434-440, 2017
PubMed
[1] Nakamura K, Shirato M, Kanno T, Lingström P, Örtengren U, Niwano Y. Photo-irradiated caffeic acid exhibits antimicrobial activity against Streptococcus mutans biofilms via hydroxyl radical formation. Sci Rep, 7: 6353, 2017
PubMed, Open Access

Conference Presentations

Apr. 2023-Mar. 2024: [3] 白土翠, 瀧田佑馬, 菅野太郎, 松浦寛, 庭野吉己, 南出泰亜, 中村圭祐． 1.6‐テラヘルツ（THｚ）レーザー照射が細菌に与える影響（ポスター発表）．日本防菌防黴学会第50回学術集会 2023年8月大阪
[2] 栗原朱, 宍戸駿一, 稲垣亮一, 原田章生, 菅野太郎, 江草宏. 紫外線照射による酸素空孔の励起を介した歯科用ジルコニアの変色（ポスター発表）．日本補綴歯科学会　第132回学術大会　2023年5月　横浜
[1] 宍戸駿一, 稲垣亮一, 菅野太郎. モノリシックジルコニアクラウンの表面結晶構造変化と残留応力の分析（ポスター発表：優秀ポスター賞）．日本補綴歯科学会　第132回学術大会　2023年5月　横浜
Apr. 2022-Mar. 2023: [7] 岡谷泰佑, 横山雄基, 宍戸駿一, 中村圭祐, 金森義明. ワイヤグリッド偏光子付き光ファイババンドルを用いた拡散反射計測による歯質判別（ポスター発表：速報ポスター賞受賞）. 第39回「センサ・マイクロマシンと応用システム」シンポジウム. 2022年11月徳島
[6] Nakamura K (Invited Lecturer). Dental application of ultraviolet-A induced photochemical and photobiological reactions. 2022 TU-HKU-FJMU International Symposium on Oral Health Sciences. Online symposium, November, 2022
[5] 中村圭祐. ヒドロキシルラジカルを応用した殺菌技術の歯科臨床応用（シンポジウム招待講演）．日本機能水学会第20回学術大会 2022年10月東京
[4] 中村圭祐. 活性酸素発生を応用した口腔細菌制御技術の歯科応用（シンポジウム招待講演）．日本防菌防黴学会第49回学術集会 2022年9月東京
[3] 宍戸駿一, 白土翠, 倉内美智子, 中村圭祐, 菅野太郎, 庭野吉己. Bacillus cereus芽胞に対する過酸化水素光分解殺菌法の殺芽胞効果（ポスター発表）．日本防菌防黴学会第49回学術集会 2022年9月東京
[2] 宍戸駿一, 宮野怜,中島琢自,松尾洋孝,岩月正人,中村圭祐, 菅野太郎, 江草宏, 庭野吉己. カテキンの光酸化反応機構の解明および活性酸素を介した殺菌活性評価（ポスター発表）．日本ポリフェノール学会第15回学術集会 2022年8月東京
[1] 宍戸駿一, 稲垣亮一, 菅野太郎. 研磨、研削、サンドブラスト処理がジルコニアの結晶構造および残留応力に及ぼす影響（口頭発表）．日本補綴歯科学会　第131回学術大会　2022年7月　大阪
2021年度: [6] Shishido S, Hua Y, Chhetri PK, Nakamura K, Svanborg P. The mechanical and microstructural properties of self-glazed zirconia (Outstanding Poster Award). International Symposium for Interface Oral Health Science 2022. Online symposium, Jan, 2022
[5] Shirato M, Nakamura K, Tenkumo T, Niwano Y, Kanno T, Sasaki K, Lingström P, Örtengren U. Treatment with hydrogen peroxide photolysis inhibits tooth demineralization caused by Streptococcus mutans biofilm. International Symposium for Interface Oral Health Science 2022. Online symposium, Jan, 2022
[4] Åkerlind K, Tu L, Nakamura K, Hong G, Örtengren U. Comparison in education and management of the caries disease between two universities (Outstanding Poster Award). International Symposium for Interface Oral Health Science 2022. Online symposium, Jan, 2022
[3] 白土翠、中村圭祐、菅野太郎、庭野吉己．過酸化水素光分解殺菌法によるう蝕治療有効性評価のための多菌種バイオフィルムモデルの検討. 第48回日本防菌防黴学会年次大会（オンライン） 2021年9月
[2] Shishido S, Miyano R, Nakashima T, Matsuo H, Iwatsuki M, Nakamura K, Kanno T, Egusa H, Niwano Y．A reaction mechanism of photo-oxidation process of catechin in relation to its bactericidal activity. Oral presentation at XXX International Conference on Polyphenols (ICP2020 Turku). Online conference, Jul. 2021
[1] Nakamura K, Tenkumo T, Aobulikasimu A, Shirato M, Shishido S, Kanno T, Niwano Y, Sasaki K, Asou Y. Improvement of bone health condition by oral administration of proanthocyanidin-rich grape seed extract in ovariectomized animals. Oral presentation at XXX International Conference on Polyphenols (ICP2020 Turku). Online conference, Jul. 2021
Apr. 2020-Mar. 2021: [2] Örtengren U, Shirato M, Lingström P, Nakamura K．Time-kill kinetic analysis of antimicrobial chemotherapy based on hydrogen peroxide photolysis. The Annual Swedish Dental Congress of 2020 (Digital Research Presentation). Nov. 2020
[1] Nakamura K (Keynote Lecturer)．Applications of a novel antimicrobial chemotherapy utilizing HO generated by H2O2 photolysis to dental treatments. 2020 TU-HKU-FJMU International Symposium on Oral Health Sciences. Online symposium, Sep. 2020
Apr. 2019-Mar. 2020: [4] 宍戸駿一．CEREC修復の適合精度に影響を及ぼす因子の検討．日本臨床歯科CADCAM学会第六回学術大会 2019年11月東京
[3] 宍戸駿一、原田章生、稲垣亮一、菅野太郎、江草宏．高透光性歯科用ジルコニアの微細構造評価．令和元年度　日本補綴歯科学会東北・北海道支部学術大会 2019年10月福島
[2] 白土翠、中村圭祐、天雲太一、菅野太郎、佐々木啓一、庭野吉己．歯周病原因菌によって汚染されたチタン表面の清浄化技術の開発：過酸化水素光分解で生成する水酸化ラジカルの応用. 第46回日本防菌防黴学会年次大会 2019年9月大阪
[1] 佐々木啓一、菅野太郎、中村圭祐、石山希里香、山田康友、白土翠、庭野吉己、萱場千恵、池田浩治、高木愛理、山口拓洋．医師主導治験におけるラジカル殺菌歯周病治療器の臨床効果の検証：無作為化比較試験. 第62回春季日本歯周病学会学術大会 2019年5月神奈川
Apr. 2018-Mar. 2019: [5] 宍戸駿一、宮野怜、中島琢自、松尾洋孝、岩月正人、中村圭祐、菅野太郎、江草宏、庭野吉己．カテキンの光酸化を介した殺菌活性と光酸化機序の解明―その2―. 第45回日本防菌防黴学会年次大会 2018年11月東京
[4] 白土翠、中村圭祐、天雲太一、菅野太郎、庭野吉己．Streptococcus mutansバイオフィルムが引き起こす歯質脱灰に対する過酸化水素光分解殺菌技術の効果. 第45回日本防菌防黴学会年次大会 2018年11月東京
[3] 中村圭祐、天雲太一、目代貴之、白土翠、石山希里香、菅野太郎、佐々木啓一、庭野吉己．カフェイン酸に対するUV-A照射で得られる殺菌作用と口腔粘膜刺激性の評価. 第45回日本防菌防黴学会年次大会 2018年11月東京
[2] 天雲太一、中村圭祐、白土翠、菅野太郎、佐々木啓一．プロタミンを付与したリン酸カルシウム系遺伝子導入剤の抗菌作用. 第45回日本防菌防黴学会年次大会 2018年11月東京
[1] 天雲太一、中村圭祐、菅野太郎、佐々木啓一．遺伝子導入剤を含有したナノハイドロキシアパタイト-コラーゲンscaffoldの開発. 第61回春季日本歯周病学会学術大会 2018年6月東京
Apr. 2017-Mar. 2018: [6] Nakamura K, Shirato M, Tenkumo T, Kanno T, Westerlund A, Örtengren U, Sasaki K, Niwano Y. Reconditioning of biofilm-contaminated titanium surface for osteoblast proliferation by hydroxyl radicals generated via H₂O₂ photolysis. International Symposium for Multimodal Research and Education in IOHS-Liaison 2018 in Sendai, Japan, Jan. 2018
[5] Tenkumo T, Saenz JRV, Nakamura K, Shimizu Y, Sokolova V, Epple M, Kamano Y, Egusa H, Sugaya T, Sasaki K. Gene transfection in vivo with bone morphogenetic protein-2 encoding DNA-functionalized calcium phosphate nanoparticle-loaded collagen scaffolds. International Symposium for Multimodal Research and Education in IOHS-Liaison 2018 in Sendai, Japan, Jan. 2018
[4] Nakamura K, Shirato M,　Kanno T, Lingström P, Örtengren U, Niwano Y. Anti-biofilm effect of hydroxyl radicals generated in UVA-irradiated caffeic acid. Presented at CED-IADR/NOF Oral Health Research Congress in Vienna, Austria, Oct. 2017
[3] Shirato M, Nakamura K, Kanno T, Lingström P, Niwano Y, Örtengren U. Comparison of antimicrobial activity of hydrogen peroxide photolysis against Streptococcus mutans biofilm with photodynamic therapy. Presented at CED-IADR/NOF Oral Health Research Congress in Vienna, Austria, Oct. 2017
[2] 宍戸駿一、宮野怜、中島琢自、佐藤恵美子、中村圭祐、菅野太郎、江草宏、庭野吉己．カテキンの光酸化を介した殺菌活性と光酸化機序の解明. 日本防菌防黴学会第44回年次大会 2017年9月豊中
[1] 中村圭祐、白土翠、菅野太郎、庭野吉己．齲蝕原因菌（Streptococcus mutans）のバイオフィルムに対する長波長紫外線照射の殺菌作用. 日本防菌防黴学会第44回年次大会 2017年9月豊中